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Boster Bio Anti-Syntaxin-6 STX6 Antibody catalog # A06586. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
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Boster Bio Anti-Syntaxin 6/STX6 Antibody Picoband® catalog # A06586-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that
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Image Search Results
Journal: PLoS ONE
Article Title: Rivastigmine Lowers Aβ and Increases sAPPα Levels, Which Parallel Elevated Synaptic Markers and Metabolic Activity in Degenerating Primary Rat Neurons
doi: 10.1371/journal.pone.0021954
Figure Lengend Snippet: Levels of low molecular weight neuronal sAPP (LMW-sAPP), high molecular weight glial sAPP (HMW-sAPP), and sAPPα were compared to levels of the presynaptic protein markers SNAP-25 and syntaxin-4, and the postsynaptic protein marker PSD-95. All values are expressed as a % of vehicle-treated cells for comparison. PSD-95 and SNAP-25 levels increased dose-dependently with rivastigmine treatment (both p<0.05), and syntaxin-4 levels increased but this change did not reach significance (7A and 7B). LMW-sAPP was increased with 5 µM rivastigmine but plateaued at the higher concentration. HMW-sAPP increased to a lesser extent at 5 µM, but was similar to vehicle at the higher concentration (7C). These data suggest that increased neuronal and decreased glial sAPP may be involved in the enhanced neuronal and synaptic marker stability that results from rivastigmine treatment, and that modulation of α-secretase may be involved in these effects.
Article Snippet: Blots of the lysates were probed with mouse-anti-SNAP-25 (Millipore), mouse-anti-PSD-95 (Antibodies Incorporated, Davis, CA),
Techniques: Molecular Weight, Marker, Concentration Assay